Praziquantel

ngwaahịa

Praziquantel

Ozi bụ isi:

Praziquantel bụ ngwakọta organic nwere usoro kemịkal C 19 H 24 N 2 O 2 . Ọ bụ anthelmintic a na-eji na mmadụ na anụmanụ. A na-eji ya agwọ ọrịa tapeworm na flukes. Ọ dị irè karịsịa megide schistosoma japonicum, fluke imeju ndị China, na Diphyllobothrium latum.

Usoro ọgwụ: C 19 H 24 N 2 O 2

Ibu ibu: 312.406

Nọmba CAS: 55268-74-1

Nọmba EINECS: 259-559-6


Nkọwa ngwaahịa

Mkpado ngwaahịa

Njirimara physicochemical

Njupụta: 1.22 g/cm3
Ebe mgbaze: 136-142°C
Ebe esi mmiri: 544.1°C
Ebe ọkụ: 254.6°C
Ntụgharị ntụgharị: 1.615
Ọdịdị: White ma ọ bụ na-acha ọcha crystalline ntụ ntụ

jiri

A na-ejikarị ya dị ka ọgwụ antiparasitic nke sara mbara maka ọgwụgwọ na mgbochi nke schistosomiasis, cysticercosis, paragonimiasis, echinococcosis, fasciococcus, echinococcosis, na ọrịa helminth.

Njirimara

Ngwaahịa a na-acha ọcha ma ọ bụ na-acha ọcha kristal ntụ ntụ.
Ngwaahịa a na-adị mfe mgbaze na chloroform, soluble na ethanol, na-adịghị ike soluble na ether ma ọ bụ mmiri.

Ebe mgbaze

Ebe agbaze nke ngwaahịa a (General Rule 0612) bụ 136 ~ 141 ℃.

udi

anthelmintics.

Ngosipụta

Ọ bụ ọgwụ sara mbara nke na-emegide trematodes na tapeworms. Ọ dị mma maka schistosomiasis dị iche iche, clonorchiasis, paragonimiasis, fasciolosis, ọrịa tapeworm na cysticercosis.

Ihe omume ọgwụ

Ngwaahịa a na-ebutekarị mkpọnwụ spastic na mwụfu nke schistosomes na tapeworms n'ime onye ọbịa site na mmetụta 5-HT. Ọ na-enwe mmetụta dị mma na ọtụtụ ndị toro eto na ndị na-eto eto. N'otu oge ahụ, ọ nwere ike imetụta ikike calcium ion permeability na sel anụ ahụ nke ikpuru, na-abawanye ụba nke calcium ion, na-egbochi reuptake nke sarcoplasmic reticulum calcium nfuli, na-abawanye ụba calcium ion ọdịnaya n'ime akwara sel nke ikpuru. ahụ, ma mee ka ahụ ikpuru kpọnwụrụ akpọnwụ wee dapụ.

Nchekwa

Debe ọkụ ma chekwaa n'ime akpa mkpuchi.


  • Nke gara aga:
  • Osote:

  • Dee ozi gị ebe a ziga anyị ya