isosorbide nitrate

Ozi bụ isi:

Aha ọgwụ: isosorbide dinitrate; 1,4:3, 6-didehydration D-sorbitan dinitrate

Nọmba CAS: 87-33-2

Usoro ihe omimi: C6H8N2O8

Ibu ibu: 236.14

Nọmba EINECS: 201-740-9

Usoro nhazi:

Ụdị emetụtara: akụrụngwa akụrụngwa; Ndị na-ahụ maka ọgwụ; Ngwa akụrụngwa ọgwụ.

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Njirimara physicochemical

Ebe mgbaze: 70C (ọkụ)

Ebe esi mmiri: 378.59°C (atụmatụ siri ike)

Njupụta: 1.7503 (atụmatụ siri ike)

Ntụgharị ntụgharị: 1.5010 (atụmatụ)

Ebe ọkụ ọkụ: 186.6±29.9 ℃

Solubility: Soluble na chloroform, acetone, ubé soluble na ethanol, ntakịrị soluble na mmiri.

Njirimara: White ma ọ bụ ọcha crystalline ntụ ntụ, enweghị isi.

Uzuoku mgbali: 0.0±0.8 mmHg na 25 ℃

Ndekọ nkọwapụta

nkọwapụta	otu	ọkọlọtọ
Ọdịdị		White ma ọ bụ ọcha crystalline ntụ ntụ
Ịdị ọcha	%	≥99%
Mmiri	%	≤0.5

Ngwa ngwaahịa

Isosorbide nitrate bụ vasodilator nke isi ọgwụ na-eme bụ ime ka ahụ dị nro vaskụla kwụsị. Mmetụta dị n'ozuzu ya bụ ibelata ikuku oxygen nke akwara obi, mee ka ikuku oxygen dịkwuo elu, ma belata angina pectoris. Enwere ike iji ụlọ ọgwụ na-agwọ ụdị ọrịa obi dị iche iche angina pectoris ma gbochie ọgụ. Enwere ike iji mmiri ntanye na-eme ihe maka ọgwụgwọ ọrịa obi mgbakasị ahụ, ụdị ọbara mgbali elu dị iche iche na mberede na maka ịchịkwa ọbara mgbali elu tupu arụ ọrụ.