7-Amino-3-cephem-4-carboxylic acid

Ozi bụ isi:

utu Bekee:

7-ANCA;7-AMOCA;(6R,7R) -7-AMIno-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylicAcid;7-NACA;7-NACA,7-ANCA;7-ANCAChemicalbook adịghị ọcha;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid

Nọmba CAS: 36923-17-8

Usoro ihe omimi: C7H8N2O3S

Arọ molikula: 200.21

Nọmba EINECS: 609-312-7

Usoro nhazi:

Ụdị njikọ: Organic intermediates; Ndị na-ahụ maka ọgwụ; Ngwa akụrụngwa ọgwụ.

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Njirimara physicochemical

Ebe mgbaze: 215-218°C

Isi ihe na-esi esi: 536.9± 50.0 °C (buru amụma)

Njupụta: 1.69± 0.1g/cm3(buru amụma)

Ntụgharị ntụgharị: 1.735 (atụmatụ)

Ebe ọkụ: 278.508°C

Solubility: Soluble na acidic aqueous solution (obere, kpụ ọkụ n'ọnụ), DMSO (obere). Njirimara: White ma ọ bụ ọcha crystalline ntụ ntụ.

Nrụgide ikuku: 0mmHg na 25°C

Ndekọ nkọwapụta

nkọwapụta	otu	ọkọlọtọ
Ọdịdị		White ma ọ bụ ọcha crystalline ntụ ntụ
Isi ọdịnaya	%	≥98.5%
Mmiri	%	≤1
Mono ngwakọ	%	≤0.5
Ngụkọta ntukọ	%	≤1

Ngwa ngwaahịa

Cephalosporin, eji dị ka etiti nke cefbutan na cefazoxime.

mmepụta

Agbakwunyere sulfuric acid (104.3mL, 1.92mol) n'ime karama atọ, wee tinye isophthalic acid (40g, 0.24mol), kpalitere ma kpoo ọkụ ruo 60 ℃, ejidere maka 0.5h, na 60% nitric acid (37.8g, ogo 0.36mol) agbakwunyere dobe na-achịkwa. Tinye ya n'ime awa 2. Mgbe mgbakwunye, mmeghachi omume nchekwa okpomọkụ na 60 ℃ maka awa 2. Jụụ n'okpuru 50 Celsius C, wee tinye 100ml mmiri. A na-eme ka ihe dị mma na okpomọkụ dị n'ime ụlọ, wụsa n'ime ihe nzacha, na-agbapụta iji wepụ acid na-ekpofu ihe, a na-asacha achicha ahụ na mmiri, na-agbanye ya ka ọ gbanwee, na ngwaahịa ọcha bụ gram 34.6, mkpụrụ bụ 68.4%.

Nkọwapụta na nchekwa

20Kg ma ọ bụ 25Kg/ ịwụ, bọket kaadiboodu, nke ejiri akwa ọcha kpuchie ya na akpa polyethylene ojii. 2℃-8 ℃ nkụ, jụụ ebe, pụọ ìhè nchekwa, irè maka 2 afọ.

Nke gara aga: 5-nitroisophthalic acid

Osote: Bromosartan biphenyl

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