7-Amino-3-cephem-4-carboxylic acid
Ozi bụ isi:
utu Bekee:
7-ANCA;7-AMOCA;(6R,7R) -7-AMIno-8-oxo-5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylicAcid;7-NACA;7- NACA,7-ANCA;7-ANCAChemicalbook adịghị ọcha;CeftizoximeImpurity9;CeftizoximeImpurity16;Ceftizoximeintermediate(7-anca);7-amino-3-cephem-4-carboxylicacid
Nọmba CAS: 36923-17-8
Usoro ihe omimi: C7H8N2O3S
Arọ molikula: 200.21
Nọmba EINECS: 609-312-7
Usoro nhazi:
Ụdị njikọ: Organic intermediates; Ndị na-ahụ maka ọgwụ; Ngwa akụrụngwa ọgwụ.
Ebe mgbaze: 215-218°C
Isi ihe na-esi esi: 536.9± 50.0 °C (buru amụma)
Njupụta: 1.69± 0.1g/cm3(buru amụma)
Ntụgharị ntụgharị: 1.735 (atụmatụ)
Ebe ọkụ: 278.508°C
Solubility: Soluble na acidic aqueous solution (obere, kpụ ọkụ n'ọnụ), DMSO (obere). Njirimara: White ma ọ bụ ọcha crystalline ntụ ntụ.
Nrụgide ikuku: 0mmHg na 25°C
| nkọwapụta | otu | ọkọlọtọ |
| Ọdịdị | White ma ọ bụ ọcha crystalline ntụ ntụ | |
| Isi ọdịnaya | % | ≥98.5% |
| Mmiri | % | ≤1 |
| Mono ngwakọ | % | ≤0.5 |
| Ngụkọta ntukọ | % | ≤1 |
Cephalosporin, eji dị ka etiti nke cefbutan na cefazoxime.
A na-etinye sulfuric acid (104.3mL, 1.92mol) n'ime karama atọ, wee tinye isophthalic acid (40g, 0.24mol), kpalie ma kpoo ọkụ ruo 60 ℃, nke 0.5h, na 60% nitric acid (37.8g, 0.36). mol) agbakwunyere iji chịkwaa ogo nrịbawanye nke droplet. Tinye ya n'ime awa 2. Mgbe mgbakwunye, mmeghachi omume nchekwa okpomọkụ na 60 ℃ maka awa 2. Jụụ n'okpuru 50 Celsius C, wee tinye 100ml mmiri. A na-eme ka ihe dị mma na okpomọkụ dị n'ime ụlọ, wụsa n'ime ihe nzacha, na-agbapụta iji wepụ acid na-ekpofu ihe, a na-asacha achicha ahụ na mmiri, na-agbanye ya ka ọ gbanwee, na ngwaahịa ọcha bụ gram 34.6, mkpụrụ bụ 68.4%.
20Kg ma ọ bụ 25Kg/ ịwụ, bọket kaadiboodu, nke ejiri akwa ọcha kpuchie ya na akpa polyethylene ojii. 2 ℃-8 ℃ nkụ, jụụ ebe, pụọ ìhè nchekwa, irè maka 2 afọ.
