2-methyl-5-nitroimidazole
Ozi bụ isi:
Aha ọgwụ: 2-methyl-5-nitroimidazole;
Aha Bekee: 2-Methyl-5-nitroimidazole;
Nọmba CAS: 88054-22-2
Usoro ihe omimi: C4H5N3O2
Arọ molikula: 127.1
Nọmba EINECS: 618-108-7
Usoro nhazi:
Ụdị emetụtara: akụrụngwa akụrụngwa; Ndị na-ahụ maka ọgwụ; Ngwa akụrụngwa ọgwụ.
Njupụta: 1.4± 0.1g / cm3
Ebe esi mmiri: 399.5± 15.0 Celsius C na 760 mmHg
Ebe mgbaze: 252-254ºC
Ebe ọkụ ọkụ: 195.4± 20.4 °C
Ọnụ ọgụgụ ziri ezi: 127.038177
PSA: 74.50000 LogP: -0.10
Ọdịdị: kristal ọcha
Nrụgide ikuku:0.0±0.9 mmHg na 25°C
Ntụgharị ntụgharị: 1.592
Ọnọdụ nchekwa: mechie na ebe dị jụụ na nkụ nke 0-6 ºC
Nkwụsi ike: ọ gaghị emebi emebi mgbe ejiri ya wee chekwaa ya dịka iwu siri dị.
| nkọwapụta | otu | ọkọlọtọ |
| Ọdịdị | Dị ka ntụ ntụ ọcha ma ọ bụ odo odo | |
| Ọdịnaya | % | ≥99% |
| Mmiri | % | ≤0.3 |
| Sulfate | % | ≤0.3 |
A na-ejikarị eme ihe na njikọ nke metronidazole, dimetazole na ọgwụ ndị ọzọ dị n'etiti.
A na-enweta ya site na nitration nke 2-methylimidazole. Tinye sulfuric acid, 2-methylimidazole na sodium sulfate n'ime ite mmeghachi omume, kpalie na ikpo ọkụ, tinye nitric acid na 150-160 ℃, gbakwunye, gbasoo mmeghachi omume ozu ahụ maka otu awa. Wepu okpomọkụ na 140 ℃ n'okpuru, mgbe agbakwunyere mmiri na amonia mmiri iji dozie pH na 3.5-4, crystallization. Nri, saa na-anọpụ iche, nkụ, 2-methyl-5-nitroimidazole.
25k kraft akwụkwọ akpa ma ọ bụ akpa akpa (58 × 110) ejiri akpa rọba kpuchie, 250kg mbupụ akpa akpa (100 × 80); Dị ka ndị ahịa chọrọ;
Nchekwa akara, echekwara na ụlọ nkwakọba ihe dị jụụ, ọchịchịrị, nkụ, nchekwa na njem kwesịrị ịdị ọkụ, iji gbochie mmebi na mmiri, nke a machibidoro iwu na ọgwụ agwakọta.
Usoro mmepụta: enwetara site na nitration nke 2-methylimidazole. Tinye sulfuric acid, 2-methylimidazole na sodium sulfate n'ime ite mmeghachi omume, kpalie na ikpo ọkụ, tinye nitric acid na 150-160 ℃, gbakwunye, gbasoo mmeghachi omume ozu ahụ maka otu awa. Wepu okpomọkụ na 140 ℃ n'okpuru, mgbe agbakwunyere mmiri na amonia mmiri iji dozie pH na 3.5-4, crystallization. Nri, saa na-anọpụ iche, nkụ, 2-methyl-5-nitroimidazole.
